PHENOL SENSITIVITY AND 'IMMUNE OVERWHELM' IN ASD, ADHD AND NEURODEVELOPMENTAL CONDITIONS

HOW DOES PST ENZYME RESEARCH OFFER CLINICAL PEARLS INTO UNDERSTANDING SYMPTOMS IN AUTISM & ADHD?

Understanding the implications in the disturbance the PST pathway offers

potential insight in many directions:

INSIGHT

1. A clearer understanding of a key metabolic and bio-chemical factor in the

development of ASD, ADHD and other neurodevelopmental symptoms

triggers

PRACTICAL SUPPORT MEASURES

2. Practical dietary and lifestyle interventions to mitigate or reduce trigger

exposure

POTENTIAL SUPPLEMENTAL SUPPORT

3. Supplemental support to improve or even heal the function of the enzyme

thus improving function in all of multiple areas that it causes symptoms.

UNDERSTANDING AGGRAVATIONS

4. Addressing and understanding a key factor in intolerance of medical,

supplemental, nutritional and homeopathic therapeutic approaches, ‘Why

the medicine doesn’t work’ or causes aggravation rather than healing

response.

SYMPTOM RELATIONSHIPS

5. Understanding at least one part of the metabolic impact of infection and

toxicity in terms of their patho-physiology in the terrain of autism.

How does toxicity impact metabolism in a way that produces loss of immune tolerance

and immune failure, or compromised ability to resist infection.

Fundamentally, treatment for symptoms should pursue :

• short term 'management' strategies,

• improved quality of life,

• and wherever possible, deep, gentle and long-lasting cure at the heart of the issue.

This requires insight into potential triggers and causes. Research into PST dysfunction offers a great deal of both insight and treatment options that cover the whole gamut of system susceptibilities associated with ASD:

• behaviour,

• sleep,

• immune function,

• neuroinflammation,

• detoxification,

• hyper or hypo sensitivity, etc

WHAT IS IMMUNE OVERWHELM AND WHY IS IT IMPORTANT?

With insight into a cause, often there are straightforward measures that can be put in place. Sometimes it is these simple steps that take a day to day situation out of the extremes and begin to give space for more effective treatment.

SENSITIVITY REACTIONS THAT 'MUFFLE' HEALING REMEDY RESPONSE

There is frequently a loss of immune tolerance that underpins ASD and ADHD cases - the metabolic results of this can contribute to a scenario where there exists an apparent 'lack of response' to well indicated interventions and remedies, ie ‘ The medicines don’t work!’ -

Frequently this is likely to be because any impact is muffled by the overwhelming immune overreaction to day to day environment and food exposures that silence or blocks the healing effects of intended treatments.

IMMUNE OVERWHELM

OR, if the immune system is in such a state of chronic and constant overwhelm from sensitivity reactions, (which is certainly the case in many children), the healing impetus of a medicine or remedy can add the overwhelm. There is IMMUNE OVERWHELM and in this state, even the push to detox, increase antioxidant enzymes, or stimulate any type of systemic healing response, can be felt as excess and produce an apparently unhelpful healing response.

Whilst we may commonly refer to aggravation as a response to a remedy that may be necessary or part of the bodies push to equilibrium, there is a common experience in these cases that reflects the state of high immune activation beneath the surface. Just as the immune response is frequently pro-inflammatory (ie cytokine response to infection), a healing response that triggers a very necessary pro- inflammatory process, may be simply too much too soon for a beleaguered and overwhelmed immune system.

Awareness of PST dysfunction as part of the puzzle allows as practical and straightforward methods to unload the system of day to day stressors, and thus begin to take it out of its state of overwhelm. From here, we can begin to employ deeper and more indicated methods to address the true causations.